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Cortisol Saliva Test - 4 Specimens

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This test provides measurements of cortisol levels across four saliva samples.

This test measures cortisol levels in your saliva. Cortisol, a hormone produced by the adrenal glands, affects almost every organ and tissue in your body. Proper cortisol levels are important in helping the body respond to stress, fight infection, regulate blood sugar, maintain blood pressure, and regulate metabolism.

What is a Cortisol Saliva Test?

The Cortisol Saliva Test works by collecting 4 samples of saliva and measuring the amounts of cortisol in each sample. If your cortisol levels are too high or too low, it may mean you have an adrenal gland disorder. These disorders can be serious if not treated.

You must get a specimen collection kit from the lab to take this test. This allows you to make the sample collections where and when it is convenient for you, without having to return to the lab to collect each of the four samples. 

Why would my doctor order a Cortisol Saliva Test?

Your provider may order this test to diagnose disorders of the adrenal and pituitary glands. These include Cushing’s syndrome, Addison’s disease, Adrenocortical Insufficiency, or Hypersecretion.

When should I order a Cortisol Saliva Test?

Your provider may wish to order a Cortisol Saliva Test if you’ve exhibited symptoms related to irregular cortisol production, such as: 

  • unexplained weight loss or gain
  • anxiety
  • chronic fatigue
  • muscle weakness
  • abdominal pain
  • skin that bruises easily
  • very high or low blood pressure 

You must follow the collection kit directions very closely to take the Cortisol Saliva Test at home. 

How do I read the results of the test?

Once you receive the results of your test, you will need to consult with your provider. Only a medical professional can advise you on the healthy ranges of cortisol in your body and help you develop a treatment plan if necessary. You can get an online consultation with a vetted, highly rated doctor through Tripment Health. 

Do my results change with age?

Normal aging is associated with cortisol changes, including changes in the structure and function of the adrenal gland. Infection, stress, pregnancy, birth control pills, and other medicines can also affect cortisol levels.

What should I expect at my appointment?

To prepare for a Cortisol Saliva Test, your provider will issue a specimen container and specific collection instructions. They may ask you to not eat, drink, or brush your teeth 30 minutes prior to collection. Because cortisol levels change throughout the day, your provider will likely recommend that your test be conducted at a specific time when cortisol levels are lower. Cortisol Saliva Tests are considered to be highly accurate, though they may be used in conjunction with additional blood, urine, or imaging tests, such as CT scans and MRIs, for an even deeper analysis. Cortisol Saliva Test results typically take 4-9 business days to process. 

How much does a test cost?

The cost of a Cortisol Saliva Test listed on Tripment Health is transparent and final – you will never be asked to pay additional fees at the testing facility, or receive a surprise bill down the road. 

Where can I find an affordable Cortisol Saliva Test near me?

Tripment Health has partnered with nearly 7,000 lab test facilities across 48 states. Finding a Cortisol Saliva Test, current procedural technology (cpt) code 18921, is easier than ever. Add the lab tests you need to your cart, then select a testing facility conveniently close to you. 


+$15 service fee

Price not includes a Physician Service Fee ($6) and a Lab Collection Fee ($9). These non-refundable fees cover the ordering and oversight of lab tests, and follow-up services when appropriate.

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  • 1. Select a test

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  • 2. Pay online

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  • 3. Go to the lab

    Visit the lab of your choice

  • 4. Get fast results online

    We will email you when results are ready, in 1–3 business days

Lab tests FAQs

No. At Tripment Health, we focus on providing transparent healthcare services to uninsured or under-insured individuals. We’ve negotiated prices directly with lab test facilities to make diagnostic lab panels available to individuals who would rather pay directly than go through a private or government-sponsored insurance carrier.

No. By purchasing a blood panel, you will not be able to submit any claim, bill, or other request for reimbursement to any insurer, third-party payer, or Government health program. However, you can use your FSA or HSA card.

You will receive a payment confirmation email, then an additional email confirming your appointment details (type of test, time and location of appointment, and QR code). You will need to present your QR code to the testing facility in order to check in.

Once your test is complete, you will receive your results within 1-3 business days.

With a blood panel, you can establish your body’s baseline values for basic health measurements like cholesterol (total, triglycerides, HDL, LDL and total cholesterol/HDL ratio), glucose and hemoglobin A1c. Additionally, depending on the blood panel you choose, you will receive data on performance measurements such as Vitamin D, Vitamin B12, Magnesium, Thyroid Stimulating Hormone, and/or Testosterone.


Your results are more than just numbers. Your results come with a personalized recommendation from one of our physicians.

No. One of our physicians will order the panels for you.

You must be 18 or over to be able to get tested.

Currently we have local patient service centers available in all states, except in NY, NJ, TX & RI.