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Cortisol, Total

  • CLIA Certified Labs
  • Best Price
  • Digital Report

Cortisol is a steroid hormone associated with immune response, metabolism, and how your body responds to stress.

  • Sample Type: Blood
  • Results: 1-6 days
  • Age: 18+

The Cortisol Total test is a laboratory test that measures the total amount of cortisol in the blood. Cortisol is a hormone produced by the adrenal glands in response to stress and plays a crucial role in regulating various physiological processes in the body, including metabolism, immune response, and stress response.

No fasting required. Stop biotin consumption at least 72 hours prior to the collection. It is recommended that collection for the CA-125 test occur at least 3 weeks after primary chemotherapy and at least two months following abdominal surgery.

Quest test codes: 367


+$15 service fee

Price does not include the Physician Service Fee ($6) and the Lab Collection Fee ($9). These non-refundable fees cover the ordering and oversight of lab tests and follow-up services when appropriate.

Next availability

Provided by Quest Diagnostics
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4.6 rating

How does it work?

  • Order Tests Online

    No doctor visit required for purchase. Choose from a wide range of panels and tests. Pay online with a credit or debit card — no insurance needed.
  • Go to the Lab for Sample Collection

    Complete your test sample collection during your scheduled appointment.
  • Get Fast Results Online

    We will email you when your results are ready. Access your Confidential Lab Record by logging in to your account. There you can view, save and print your results.

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Frequently Asked Questions

The Cortisol Blood Test works by collecting a blood sample and measuring levels of cortisol, a hormone produced by the adrenal gland. Cortisol helps regulate blood pressure, immune response, and even stress. 

Your provider may order a blood test for cortisol to diagnose certain adrenal and pituitary gland conditions, such as Cushing’s syndrome, Addison’s disease, and adrenocortical insufficiency or hypersecretion.

Your provider may wish to order a Cortisol Blood Test if you’ve exhibited the following symptoms:  

  • Abnormally high or low blood pressure
  • Sudden weight gain or loss
  • Purple abdominal streaks 
  • Fatigue 
  • Abdominal pain
  • Dark patches on the skin. 

You cannot take a Cortisol Blood Test at home — this test can only be administered by a medical professional at a licensed testing facility. 

Once you receive the results of your blood test for cortisol, you will need to consult with your provider. Only a medical professional can advise you on the results and help you develop a treatment plan if necessary. 

Hormone levels tend to fluctuate with age. Changes in sleep patterns can also cause slight shifts in cortisol levels. However, significant changes in cortisol are often due to adrenal or pituitary gland problems.

There are no special requirements for the Cortisol Blood Test, though it is not recommended for people who are currently taking prednisone/prednisolone, due to cross-reactivity. Your provider will draw a blood sample from a vein in your arm. Cortisol Blood Test results typically take 2-3 business days to process. 

The cost of a Cortisol Blood Test listed on Tripment Health is transparent and final — you will never be asked to pay additional fees at the testing facility, or receive a surprise bill down the road. 

Tripment Health has partnered with nearly 7,000 lab test facilities across 48 states. Finding a Cortisol Blood Test, current procedural technology (cpt) code 367, is easier than ever. Add the lab tests you need to your cart, then select a testing facility conveniently close to you.